Paola Pedrelli, PhD

Dr. Pedrelli is an Associate Director of the Depression Clinical Research Program at Massachusetts General Hospital and an Associate Professor of Psychiatry at Harvard Medical School. Dr. Pedrelli's research focuses on several key areas. She is a leading scientist in the development of digital tools for the long-term monitoring of depression, leveraging artificial intelligence and wearable and mobile sensors. Her commitment to improving clinical care for depression drives her research into innovative treatment methods. She has developed several face-to-face cognitive behavioral therapy approaches for depression, both in isolation and in conjunction with heavy episodic drinking. Additionally, she has conducted clinical trials on novel digital health interventions for depression. More recently, her work has centered on investigating the effectiveness of ketamine-based treatments for depression and suicidal thoughts and behaviors, as well as the underlying mechanisms of these conditions.
Dr. Pedrelli's research has been supported by the National Institutes of Health (NIH), the Defense Advanced Research Projects Agency (DARPA), and various foundations and industry partners. She has been invited to speak at national and international scientific meetings and has been featured in numerous media outlets. To date, she has authored more than 70 peer-reviewed publications and chapters.